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Investigators believe the cigarettes, sealed in cardboard boxes, were manufactured in factories outside Alberta and then smuggled into the province by truck

PMID 31825092

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Curr Pharm Des 20(22):35793594 Kiowski W et al (1994) Diminished vascular response to inhibition of endothelium-derived nitric oxide and enhanced vasoconstriction to exogenously administered endothelin-1 in clinically healthy smokers