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CellROX expression was calculated as the area of CellROX normalized to DAPI area, to account for differences in cell number
The broad distribution in brain of the processes regulating oxidative stress and mediating glutamatergic neurotransmission may explain the wide range of disorders in which both have been implicated
Another important isozyme, GPx4, has been linked with regulating the radiation-induced ferroptosis mode of cell death [67]
This phase is followed by the condensation of six isopentenyl pyrophosphate molecules to form squalene, then undergoes cyclization catalyzed by squalene monooxygenase (SM), producing 2,3-oxidosqualene, which is further processed through multiple enzymatic steps to generate cholesterol [25, 28] (Fig