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Disclosure of interest: Marina Guasch-Jimnez: received a research grant from the Cerebrovascular diseases group of the Spanish Neurology Society (Beca Proyecto Ictus 2022) Nicols Lpez-Hernndez: nothing to disclose Jess Juega: nothing to disclose Irene Alcobendas-Liern: nothing to disclose Emilio Rodrguez-Castro: nothing to disclose Sebastin Garca-Madrona: nothing to disclose Patricia de la Riva: nothing to disclose Manuel Medina-Rodrguez: nothing to disclose Patricia Calleja: nothing to disclose Roberto Muoz-Arrondo: nothing to disclose Blanca Serrano-Serrano: nothing to disclose Patricia Martnez-Snchez: nothing to disclose Herbert Tejada-Meza: nothing to disclose Laura Llull: nothing to disclose Pol Camps-Renom: nothing to disclose

While first explored as a treatment for shielding the stomach lining, it has subsequently earned awareness due to its restoration abilities in diverse tissues such as tendons

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However, B12 plays a specific role in the growth of new hair

This allows researchers to isolate metabolic signaling effects without confounding endocrine responses, making AOD 9604 a useful model for studying localized metabolic regulation