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Accumulation of leukocytes in the microvasculature, which prevents reperfusion, deteriorates tissue damage by producing ROS [34]

Studies have shown that it can promote healing by improving blood flow and reducing inflammation, particularly in sports-related injuries such as muscle or tendon tears

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In light of these findings, the safety and efficacy profile of RIF during TB treatment can be altered in smokers because of the concomitant induction of CYP450 enzymes mediated by PAHs