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178,179,180 In 2004, the FDA approved the first aptamer drug, pegaptanib (Macugen), to treat choroidal neovascularization caused by neovascular age-related macular degeneration (AMD)

In conclusion, while the future of ED treatments looks promising with these innovative therapies, it's crucial to remember that many are still in the nascent stages of research

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The amide nitrogen and protons of FOXO4 FHD and p53 TAD have been assigned previously 64,65