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115 As CAN progresses, patients may experience resting tachycardia, exercise intolerance, orthostatic hypotension, and silent myocardial ischemia

Both may support the liver's stores of glutathione

CellTox Green Dye binds to DNA of cells with impaired membrane integrity and exhibits increased fluorescence

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In support of this, shGDH1 cells exhibited reduced expression of mitochondrial electron transport chain (ETC) subunits and lower respiratory capacity, which could be greatly recovered by exogenous -KG (Supplementary Fig