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Alternatively activated macrophages induced by nematode infection inhibit proliferation via cell to cell contact
Important: Milk thistle is not a substitute for medically prescribed treatment for liver disease
These hallmarks include sustained proliferative signaling, evasion of growth suppressors, resistance to cell death (apoptosis), induction of ferroptosis (a form of cell death caused by iron accumulation and oxidative stress), angiogenesis (formation of new blood vessels to supply tumors), activation of invasion and metastasis, deregulation of cellular energetics, immune evasion, conferring genome instability and mutation, and tumor-promoting inflammation [135,136,137]