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This article covers the biological mechanisms BPC-157 targets in reflux pathology, the preclinical evidence base for gastric mucosal protection, the absence of human clinical trials, and what researchers should understand about peptide purity and storage when designing GERD-related studies

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BPC-157, originally isolated from human gastric juice in the 1990s, is a 15-amino acid peptide with remarkable stability and cytoprotective properties