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It falls under the S0 category of Non-Approved Substances, which is a catch-all classification for any pharmacological substance that isnt approved for human therapeutic use and is not addressed elsewhere on the list

Originally derived from a specific fragment of Human Growth Hormone (hGH), this synthetic analog was engineered to isolate the fat-burning properties of growth hormone without triggering the unwanted systemic effects often associated with the full-length molecule

10.1016/j.talanta.2023.124482 31 KuzminskiA

Despite the promising efficacy observed in Th- MYCN -derived 3D spheres, administration of the compounds resulted in gastrointestinal toxicity, including blocked intestine and stomach enlargement, necessitating early termination of the experiment

(Scientific Reports, 2021) reported that NNMT inhibition plus a lean-diet substitution lowered body weight, fat mass, and liver fat beyond either intervention alone