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Autophagy in neurodegenerative diseases: from mechanism to therapeutic approach

doi: 10.3389/fonc.2023.1331671 Received 01 November 2023 Accepted 22 November 2023 Published 12 December 2023 Volume 13 - 2023 Edited by Qingbin Cui, University of Toledo College of Medicine and Life Sciences, United States Reviewed by Yang Tian, University of Arkansas, United States Xiaolin Qian, Southern Research Institute, United States Huang Yangyu, Sun Yat-sen University Cancer Center (SYSUCC), China Updates Copyright 2023 Tang, Yang, Pan, Ren, Chen, Jin, He and Zeng

Its therapeutic potential extends beyond managing hyperuricemia, demonstrating efficacy as a URAT1 and GLUT9 inhibitor, especially in cases of renal impairment

Caveat : one is a targeted single-enzyme block

Clinical Trials Multicenter, randomized controlled trial: To verify the efficacy and safety of AOD 9604 in humans