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Ovarian endometriosis (OEM) has the potential to progress to ovarian cancer ( Reduced ovarian reserve and follicle quality, changes in normal pelvic physical environment, decreased endometrial receptivity, and immunological dysfunction are the main reasons for EMS impeding female fertility

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One-carbon metabolism and the transsulfuration pathway contain many allosteric interactions by which substrates in one part of the pathway affect the activity of distant enzymes