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Identification of post-mitotic oligodendrocytes incapable of remyelination within the demyelinated adult spinal cord

Jastreboff et al., NEJM 2023)

How PcG complexes get recruited to the Sox2 promoter during neuronal differentiation is not known

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This is important for cancer because collagen has been demonstrated to stabilize the extracellular matrix, which effectively prevents tumor cells from penetrating surrounding tissues