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GSH and GSH-rich YE prevent apoptosis and inflammation in alcoholic rats The pro-apoptotic protein Bax was upregulated in the rats treated with ethanol, while the anti-apoptotic protein Bcl-2 was downregulated

10.1016/S0140-6736(00)05183-7

341,342 A-800141 has demonstrated anti-angiogenic and anti-tumor activity in multiple xenograft models, including neuroblastoma, colon cancer, prostate cancer, and B-cell lymphoma