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On the other hand, FGF21 appears to augment catabolic hormone signalling under conditions of inadequate energy intake, for example by increasing adrenal gland sensitivity to adrenocorticotropic hormone by upregulating levels of steroidogenic proteins (105)

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Metabolic oxidative stress elicited by the copper(II) complex [cu(isaepy)2] triggers apoptosis in SH-SY5Y cells through the induction of the AMP-activated protein kinase/p38MAPK/p53 signalling axis: evidence for a combined use with 3-bromopyruvate in neuroblastoma treatment