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At the molecular level, an increased protein level of claudin-2, a pore-forming claudin, was demonstrated in comparison to healthy controls, although these pores are of insufficient size to allow diffusion of bacterial products such as LPS in decompensated cirrhosis (4)

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Renal Physiol

(2020) 16:e1008629

Oral administration to diet-induced-obese mice for ~10 days reduces fat mass without altering food intake, decreases adipocyte size, restores insulin sensitivity, and increases adipose NAD and SAM levels [2]