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In agreement with our hypothesis, the administration of TAT-DAT NT also rescues the hyperactivity, and improves spontaneous alternation behavior of spontaneously hypertensive rats (SHR) in a Y-maze, a commonly used animal model of ADHD

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In principle, decreased extracellular potassium entails myocardial hyperexcitability, with the potential to develop re-entrant arrhythmias in the skeletal muscle, hyperpolarization of the resting membrane potential, and a greater-than-normal stimulus for depolarization of the membrane in order to initiate an action potential [106]