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Therefore, VISTA inhibition could serve as a double-edge strategy to overcome MDSC-driven immune resistance, fostering robust antitumor immunity in otherwise resistant cancers [129]

The oxidative stress-induced weakening of the fibrous cap covering the plaque, due to the degradation of extracellular matrix components by matrix metalloproteinases (MMPs), is a key factor in plaque instability [75]

Alvarez MA, Cabre E, Lorenzo-Zuniga V, Montoliu S, Planas R, Gassull MA

In fact, in one 6 month study, participants were given either 250 mg per day or 1,000 mg per day of reduced glutathione

During acute asthma exacerbations, glutathione levels in the exhaled breath condensate of children were found to be lower than those in the control subjects