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A review team from Poland, for example, suggested that future studies should focus on identifying possible side effects

In placebo-controlled trials of semaglutide injection for weight management, headache (14%), fatigue (11%), and dizziness (8%) were reported in treated patients

No cancer cases have been attributed to these peptides in research or widespread use, but caution is warranted in cancer populations

The lack of immunogenicity has practical implications: the peptide can be used for extended periods without loss of efficacy due to antibody neutralization, there is minimal risk of allergic or hypersensitivity reactions, and repeated treatment cycles are supported as prior exposure does not sensitize the immune system

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