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Aside from RUO sales by chemical companies mostly marketing directly to physician practices and/or consumers for human use which is not permitted, others try to operate at risk in this somewhat Grey Market

(2016) reviewed 54 studies and found that prolotherapy consistently reduced pain and improved function in various ligament injuries

For example, scientists can use 10mL of bacteriostatic water and aim for a concentration of 1mg/mL, thus making calculations considerably easier

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