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Moreover, most abnormalities in the testicular microenvironment and germline gene expression, including metabolic alterations, apoptosis, hypoxia, and oxidative stress, showed improvement following nicotine cessation

Anyway, the answer is B

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Dear Editor, The EU Tobacco Products Directive (TPD) 2014/40/EU sets out measurement methods for ingredients and emissions levels for tobacco products (Articles 3 and 4) and regulates ingredients (Article 7) 1

How many people die from smoking in Iran each year