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The label starts at 2.5 mg weekly, long-duration obesity evidence starts at 5 mg, and registered human activity has been measured as low as 1 mg in an early diabetes study. Each number answers a different question

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[DOI] [PubMed] [Google Scholar] Sekiya A, Okano-Kosugi H, Yamazaki CM, Koide T (2011) Pigment epithelium-derived factor (PEDF) shares binding sites in collagen with heparin/heparan sulfate proteoglycans