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It has also been observed that the addition of exogenous MOTS-c increases the level of myocardial MOTS-c, which activates AMPK (33)

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These interactions can happen even with small amounts of alcohol, making any combination potentially life-threatening

These findings are important in research settings because they allow investigators to study how amylin-pathway activation may interact with other metabolic hormone systems to influence glucose-related biomarkers and overall metabolic state