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Q J Med 65:811821 Guerreiro N, Staedtler F, Grenet O, Kehren J, Chibout S-D (2003) Toxicogenomics in drug development

The small intestine and liver, as the main organs for food absorption and metabolism, are particularly vulnerable to toxin damage and can affect the health, immunity, and growth performance of pigs

The mechanism may also be relevant in brain since GSH in some brain regions is responsive to dietary sulfur amino acid supply and to the pro-cysteine drug, L-2-oxothiazolidine-4-carboxylate

Their approach includes evaluating environmental exposures, dietary factors, and lifestyle habits that may be impacting metabolic balance