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Primary endpoints should center on pain and function Knee Injury and Osteoarthritis Outcome Score (KOOS), Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), Patient-Reported Outcome Measurement Information System (PROMIS) scores), structure (MRI evaluation with delayed gadolinium-enhanced MRI of cartilage (dGEMRIC) when appropriate), and time to milestones (return to sport)

The acetate form is particularly sensitive to degradation and should be used within a short timeframe, while the more stable arginine form has a longer refrigerated shelf life

It does not interfere with peptide structure or biological activity, ensuring that the compound remains stable and effective from the moment of reconstitution until the final dose

Adult-born neurons are necessary for extended contextual discrimination

Storage requires refrigeration between 36 and 46 degrees Fahrenheit