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When AOD-9604 activates these receptors in fat tissue, it triggers localized lipolytic responses without sending signals to the brains feeding centers

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[73] [74] [75] It is synthesized by some bacteria in the gut microbiota in humans and other animals, but it has long been thought that humans cannot absorb this as it is made in the colon, downstream from the small intestine, where the absorption of most nutrients occurs

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