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Leveraging empirical approaches along with advances in information technology, such as computational drug discovery and network-based pharmacology, may facilitate the identification of novel candidate compounds and accelerate preclinical-to-clinical translation

Mechanism-based dosing principles Match intensity to pathology severity: Mild early disease may respond to conservative dosing (BPC-157 200mcg, GHK-Cu 1mg)

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Ltx1, a mouse locus that influences the susceptibility of macrophages to cytolysis caused by intoxication with Bacillus anthracis lethal factor, maps to chromosome 11

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