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Gut health responds fastest: Patients with SIBO residual symptoms, chronic GI distress, or post-antibiotic gut damage typically report meaningful improvement in GI symptoms within the first 30 days

In keeping with this observation, here we unveil a crucial role of GSH in lipid production, as the synthesis of GSH, specifically in the liver, is required for sustaining physiological circulating triglyceride levels (an important energy source) and adipose tissue homeostasis under standard dietary regimen

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These findings are supported by (i) the decreased GPx1 mRNA in intestinal macrophages, and (ii) the decreased GPx1 protein observed in biopsies from inflamed gut regions from individuals with CD, although the immunohistochemistry did not co-stain for macrophage markers