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This was associated with the inhibition mitochondrial permeability transition pore opening and increased resistance of the isolated heart to ischemia/reperfusion in these animals

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I am not convinced the data is fully there yet." Tatem said he expects the hearings to be a "hard-fought battle," but hopes committee members will consider what he described as real-world data from tens of millions of doses administered between 2014 and 2023

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