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The cells were incubated for 96 h and additives were changed every 24 h

AMPK-mediated senolytic and senostatic activity of quercetin surface functionalized Fe(3)O(4) nanoparticles during oxidant-induced senescence in human fibroblasts

In response to the AS + FeNP treatment, there was a remarkable increase in dihydroquercetin, naringenin, kaempferol, dihydrokaempferol, and quercetin compared to the AS treatment (Fig

Both groups reached the same maintenance dose, but the escalated group achieved greater weight loss (-17.1% vs -15.7%) with fewer gastrointestinal adverse events

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