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a ) Data are presented as box plots min-max (median), cytosolic fraction at 3 M, tGSH ( Trkb Penk-WT 1.0 0.03

* 1 5-FU, 5-fluorouracil

First isolated from human plasma albumin in 1973, GHK-Cu forms a high-affinity chelate with cupric ions (Cu), creating a bioavailable complex that triggers tissue repair signalling across multiple organ systems

This treatment was associated with severe toxicities in several systems, but only hepatotoxicity was thought to be associated with the addition of retinoids

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