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We observed a reduction in insulin, glucose, HOMA-IR, triglyceride, leptin, and several oxidative stress and inflammation biomarker levels and an increase in high-density lipoprotein and adiponectin levels at the end of 4 th week during 4-week intermittent fasting, however, these parameters did not reach statistical significance

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For purposes of recruit-ment, drug-resistant epilepsy was defined as having at least two or more seizures per month despite at least two anticonvulsant medication trials