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140 In contrast, growth of the CT-2A Astrocytoma in these mice was not influenced by an unrestricted KD containing 17E% protein, 141 but significantly reduced on a calorically restricted KD containing only 8E% protein, along with significant reductions in blood glucose and IGF-1

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For over two decades [50-58], new antineoplastic and genotoxic compounds were synthesized and reported