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Significant progress has been made in lowering the prevalence of bacterial infections and sepsis thanks to the widespread use of the pneumococcal vaccine and the prophylaxis of penicillin in children [48]

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Wearable biosensors (e.g., ActiGraph, Biofourmis) and mobile health (mHealth) applications (e.g., Apple ResearchKit, Google Fit) support real-time home-based monitoring of vital signs, medication adherence, and disease progression