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In another RCT ( n = 80), prolonged-release melatonin (PRM 2-mg) therapy showed a significant improvement in sleep hours and reduction in delirium episodes among hospitalized insomniac COVID-19 patients 668

CRC-infiltrating Th17 cells induced the expression of G-CSF by CAF leading to the recruitment to the TME of CD11b + Gr1 + myeloid cells endowed with pro-angiogenic features, and thus promoting resistance to VEGF blockade therapy (137)

Ferroptosis, but not necroptosis, is important in nephrotoxic folic acid-induced AKI

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