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Lower doses of the nanoparticle-based formulation showed enhanced efficacy, with in vivo toxicity studies confirming its safety at the tested levels (466)

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Because the GPX4 enzyme (which relies heavily on active glutathione to protect cell membranes) is impaired, the excess ROS molecules begin attacking the lipids that form the mitochondrial membranes

Jing B, Wang T, Sun B, Xu J, Xu D, Liao Y, et al

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