None of these failure modes are problems with the molecule itself
Protocol design and informed consent dose, frequency, route, expected timeline, monitoring plan, and a clear acknowledgment that BPC-157 is not an FDA-approved finished drug
Although TRP14 can reduce cystine in vitro (Pader et al, 2014) it is unknown whether TRP14 has this role in vivo, and it should be noted that although several Trx-fold proteins can catalyze reduction of cystine when directly assayed, this does not necessarily suggest they have that role in a physiological cell context
Georgescu D, Ancusa OE, Georgescu LA, Ionita I, Reisz D
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