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However, inhibitors of autophagy, necroptosis and apoptosis only partially improved survival substantially, suggesting that ferroptosis is essential for DOX-induced cardiomyopathy and mortality in mice [91]
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doi: 10.1212/NXG.0000000000000393 111
Large-scale postmortem analyses indicate that cerebrovascular pathology occurs in approximately 80% of AD casesa prevalence markedly higher than in other neurodegenerative disorders such as Parkinsons disease, frontotemporal dementia, and Lewy body diseasehighlighting a potentially distinctive role of vascular dysfunction in AD pathogenesis (161)
However, the abnormal UA level may be is correlative with many diseases
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