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The results indicated that retinal lesions were significantly linked to kidney function impairment in CKD patients, and the elevated MDA levels and reduced GSH levels of ferroptosis biomarkers suggest that ferroptosis might play a key role in the initiation and progression of retinal lesions, with MDA and GSH potentially serving as early biomarkers

The acetyl group prevents its oxidation and increases its plasma stability

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(4) Homocysteine Remethylation to Close the Methionine Cycle The reconversion of homocysteine to methionine is driven by methionine synthase, which transfers a methyl group from 5-methyltetrahydrofolate to homocysteine

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