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In the 1880s, several northern states pushed the minimum age to 16 years old

According to the WHO statement on heated tobacco products and the US FDA decision regarding IQOS, reducing exposure to harmful chemicals in HTPs does not render them harmless, nor does it translate to reduced risk to human health

Cigar smoke contains many types of pollutants, including fine particles (particulate matter), volatile organic compounds (VOCs), and heavy metals

The increase in heart rate and calcium transient amplitude reduction observed after chronic exposure to cigarette smoke was not evident under acute nicotine challenge (Fig

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