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Polyphyllin B inhibited STAT3/NCOA4 pathway and restored gut microbiota to ameliorate lung tissue injury in cigarette smoke-induced mice

Especially among young people, as well as addressing the higher addiction rates linked to menthol cigarettes

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They proposed this on the theory that the promotion of low-tar-and-nicotine cigarettes was less objectionable to opponents of cigarette advertising than the promotion of the high-tar-and-nicotine variety