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This produces a gradual rise in plasma concentration, peaking somewhere between 8 and 72 hours after injection, followed by a slow decline over the next several days

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Other related diseases such as fontal temporal dementia (FTD) appears to have overlap both with AD and ALS, and is commonly related with TDP-43 and C9ORF72 mutations of ALS (Warren et al., 2013), although there is evidence for TDP-43 involvement in AD, it appears to take a different progression pattern compared to ALS and FTD (Meneses et al., 2021), which suggests distinct disease mechanisms at play

Mieyal, Dysregulation of Glutathione Homeostasis in Neurodegenerative Diseases