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It acts as an amylin receptor agonist, activating AMY1, AMY2, and AMY3 receptors heterodimers of the calcitonin receptor with receptor activity-modifying proteins (RAMPs) to produce satiety signaling, gastric emptying inhibition, and glucagon suppression

doi: 10.1083/jcb.201003122

Immediately before the analysis, the tissues were homogenized using a Dounce homogenizer containing ice-cold homogenization buffer (0.1% Triton X-100 and 0.6% sulfosalicylic acid dissolved in 0.1 M potassium phosphate buffer with 5 mM EDTA disodium salt, pH 7.5)

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