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Strain isolation and cell-based studies indicate that Ruminococcus_E bovis , which is significantly downregulated in the rumen of ketotic cows, can provide gluconeogenic precursors such as alanine, thereby promoting hepatic glucose production and reducing ketone formation 59

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Increased levels of 4-hydroxynonenal and acrolein, neurotoxic markers of lipid peroxidation, in the brain in Mild Cognitive Impairment and early Alzheimer's disease

However, cyanide compounds produced during amygdalin decomposition caused important side effects when amygdalin was utilized (236) ( Table 2 )