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Further analysis showed that especially upregulation of nuclear HDAC5 was significantly associated with a reduced disease-free survival and overall survival [48]

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On the other hand, as for the GSH spectrum, the absorption bands at around 3000 cm 1 were due to the OH stretching band, 2900 cm 1 was due to the aliphatic CH stretching, 1441, 1388 and 1324 cm 1 were due to CH bending vibrations, and also the combination band of OCH and COH deformation is calculated from 1441 to 1324 cm 1