BCRP exhibits broad substrate specificity and accepts diverse chemical space, as do other ABC transporters
It is widely known for its estrogen-like activity and exhibits a broad spectrum of pharmacological effects, including anticancer, anti-inflammatory, anti-osteoporotic, neuroprotective, and hepatoprotective properties (Deng et al., 2021
A substantial body of research links elevated IGF-1 activity and IGF-1R signaling to the proliferation and survival of many tumor types, and epidemiological studies have associated higher circulating IGF-1 with increased risk of certain cancers
Ultimately, if youre interested in any of the potential benefits weve discussed perhaps you have high blood pressure, glucose issues, fertility concerns, etc
[DOI] [PMC free article] [PubMed] [Google Scholar] 68.Abd El Aziz M., Cahyadi O., Meier J.J., Schmidt W.E., Nauck M.A