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In some embodiments, the otic formulation or composition comprises between about 0.01% to about 10% by weight of the viscosity modulating agent(s)

doi: 10.1038/s41598-018-25054-y 167 KorbutAITaskaevaISBgatovaNPMuralevaNAOrlovNBDashkinMVet al

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pineal peptide tetrapeptide CAS NUMBER 307297-39-8 MOLECULAR FORMULA C 14 H 22 N 4 O 9 MOLECULAR WEIGHT ~390.35 g/mol STRUCTURE Synthetic tetrapeptide PEPTIDE SEQUENCE H-Ala-Glu-Asp-Gly-OH CHEMICAL STRUCTURE Molecular Formula : C 14 H 22 N 4 O 9 Source: PubChem Mechanism of Action Epithalon functions by upregulating telomerase reverse tranceiptase (TERT) activity in somatic cells, which promotes telomere elongation and chromosomal stability

Citation: Maar, K., Maar, M., & Maar, T