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Abstract The cause of insulin resistance in obesity and type 2 diabetes mellitus (T2DM) is not limited to impaired insulin signalling but also involves the complex interplay of multiple metabolic pathways

Despite the pervasive role of miRNAs in essential biological processes and as promising therapeutic targets, there is only a few dedicated reviews on their role in regulation of the IGF-1 signaling pathway ( Table 1 ) and discuss their potential role as therapeutic agents

Responses to reward in monkey dorsal and ventral striatum

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