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For severe cases, the first dose is usually 1,000 mcg given intramuscularly every day or every other day for a week or two

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For adults in the UK, the standard dietary reference intake is 1.5 micrograms (g) daily for maintenance of normal health

Because a large number of comparisons were performed on the relative abundance data, main effect results from these analyses also underwent a BenjaminiHochberg false discovery rate (FDR) correction for multiple comparisons, and instances where a result was significant after this correction have been duly noted