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At the same time, it is also crucial for cancer cell metabolism and chemoresistance (Zhang et al
[00:13:00] Um, you look at the, theres some, uh, stock trackers, um, that actually made like a sort of index of all the public companies
analysed the whole saliva of patients with CD and found that the saliva was oxidatively stressed with increased values of nitric oxide and lipid peroxide markers as well as decreased antioxidant power assessed by ferric reducing ability (50)
Validating these findings, we show that deletion of the mitochondrial pyruvate carrier, which is known to decrease TCA cycle activity and protect the liver from diet-induced injury, also diminished NADPH, elevated glutathione oxidation, and alleviated ER stress
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