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Common hypotheses point to genetic predisposition plus environmental triggers

Injection delivery is the only reliable way to maintain therapeutic levels for patients with absorption issues or rapid elimination

Bruhn O, Regenhard P, Michalek M, Paul S, Gelhaus C, Jung S, Thaller G, Podschun R, Leippe M, Grtzinger J, Kalm E: A novel horse -defensin: gene transcription, recombinant expression and characterization of the structure and function

"Homocysteine and MTHFR Mutations." Circulation

At the end of the study, the percentage of remaining vitamin B 12 for these formulations was as below: F13 A (60.5%), F14 A2 (73.4%), F14 C1 (78.6%), F14 A1 (80.5%), F14 C2 (85.5%) (Figure 5)